Inactive users. What should we do with them?

I've looked through the database of users and I've noticed there are around 50 members who have signed up and never logged in even once. There are a lot of people that sign up for the site but never upload anything. I am looking for suggestions on what to do.

Should I state when people create their account that they must activate it within a month or the account will be deleted?

Or maybe inactivity for a whole month and they should receive a warning or something.

Maybe people are just forgetting that they signed up. Or maybe the email with their password is going into their junk folder. I don't know what it is but we need to do something about it.

How about a monthly newsletter that features the best artwork and writing of the month that will also work as a reminder to people who signed up that they have an account.

Any ideas? :ponders: